Nociceptive thermal threshold testing in horses – effect of neuroleptic sedation and neuroleptanalgesia at different stimulation sites

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Nociceptive thermal threshold testing in horses – effect of neuroleptic sedation and neuroleptanalgesia at different stimulation sites

BACKGROUND Aim of the study was to compare the effect of neuroleptic sedation with acepromazine and neuroleptanalgesia with acepromazine and buprenorphine on thermal thresholds (TT) obtained at the nostrils and at the withers. The study was carried out as a randomized, blinded, controlled trial with cross-over design. Thermal thresholds were determined by incremental contact heat applied to the...

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Painful diabetic neuropathy (PDN) is characterized by hyperalgesia i.e., increased sensitivity to noxious stimulus, and allodynia i.e., hypersensitivity to normally innocuous stimuli. Hyperalgesia and allodynia have been studied in many different rodent models of diabetes mellitus. However, as stated by Bölcskei et al, determination of "pain" in animal models is challenging due to its subjectiv...

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ژورنال

عنوان ژورنال: BMC Veterinary Research

سال: 2013

ISSN: 1746-6148

DOI: 10.1186/1746-6148-9-135